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Opioid-Analgetika: Chemie und Rezeptoren von Alan F. Casy (englisch) Hardcover B-
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eBay-Artikelnr.:353356538466
Artikelmerkmale
- Artikelzustand
- Topic
- Chemistry
- ISBN-13
- 9780306421303
- ISBN
- 9780306421303
- Subject Area
- Science, Medical
- Publication Name
- Opioid Analgesics : Chemistry and Receptors
- Publisher
- Springer
- Item Length
- 9.2 in
- Subject
- Neuroscience, Life Sciences / Biochemistry, Pharmacology
- Publication Year
- 1986
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Weight
- 72.3 Oz
- Item Width
- 6.1 in
- Number of Pages
- Xvi, 518 Pages
Über dieses Produkt
Product Identifiers
Publisher
Springer
ISBN-10
0306421305
ISBN-13
9780306421303
eBay Product ID (ePID)
128071
Product Key Features
Number of Pages
Xvi, 518 Pages
Language
English
Publication Name
Opioid Analgesics : Chemistry and Receptors
Publication Year
1986
Subject
Neuroscience, Life Sciences / Biochemistry, Pharmacology
Type
Textbook
Subject Area
Science, Medical
Format
Hardcover
Dimensions
Item Weight
72.3 Oz
Item Length
9.2 in
Item Width
6.1 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
86-001520
Dewey Edition
19
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
615/.783
Table Of Content
1. Introduction.- 2. 4,5-Epoxymorphinans.- 3. Morphinans.- 4. Benzomorphans.- 5. Arylmorphans and Related Compounds.- 6. Pethidine and Related 4-Phenylpiperidine Analgesics.- 7. Further Analgesics Based on Piperidine and Related Azacycloalkanes: Prodines, Promedols, Profadol, and Their Derivatives.- 8. Fentanyl and the 4-Anilinopiperidine Group of Analgesics.- 9. Methadone and Related 3,3-Diphenylpropylamines.- 10. Enkephalins, Endorphins, and Other Opioid Peptides.- 11. Miscellaneous Groups of Analgesics.- 12. Antagonists, Dualists, and Kappa Agonists.- 13. Opioid Receptors: Facts and Speculations.
Synopsis
The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal- gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono- logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability., The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.
LC Classification Number
RM300-666
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