Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.
Produktkennzeichnungen
Herausgeber
Jianglin f.a.n., Louis-Marie Houdebine
ISBN-10
9048122260
ISBN-13
9789048122264
eBay Product ID (ePID)
73066833
Produkt Hauptmerkmale
Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
Vi Seiten
Verlag
Springer-Verlag Gmbh, Springer Netherland
Publikationsname
Rabbit Biotechnology
Autor
Louis-Marie Houdebine, Jianglin Fan
Format
Gebundene Ausgabe
Erscheinungsjahr
2009
Zusätzliche Produkteigenschaften
Hörbuch
No
Item Length
24cm
Item Height
1cm
Item Width
16cm
Item Weight
366g
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