This book contains reviews by a renowned group of clinicians and scientists, which consider in great depth the potential involvement of neurogenic inflammation in the pathogenesis of migraine and inhibition of this putative mechanism as a possible mode of action of antimigraine medications. The authors carefully consider current and future potential therapeutic approaches for the abortive as well as preventive treatment of migraine. The pioneering work by Professor Michael A. Moskowitz's group at Harvard gave rise to the "neurogenic hypothesis" of migraine pathogenesis and to an intel lectual framework for many aspects of migraine research through a detailed phar macological characterization of the trigeminovascular system. This knowledge then spurred detailed research worldwide into the roles of the dural vasculature, trigem inal nerve fibers, and sensory neuropeptides, such as substance P and calcitonin gene-related peptide, in migraine. Similar in-depth investigations have not been made of the role of the seventh cranial parasympathetic nerves but this area war rants further study because of its potential for interactions with the trigeminovas cular system and its clear involvement in cluster headache.
Produktkennzeichnungen
Herausgeber
Egilius L. H. Spierings, Margarita DEL RIO Sanchez
ISBN-10
303489449x
ISBN-13
9783034894494
eBay Product ID (ePID)
168421133
Produkt Hauptmerkmale
Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
188 Seiten
Verlag
Birkhäuser Basel, Springer Basel
Publikationsname
Migraine: A Neuroinflammatory Disease?
Autor
Margarita del Rio Sanchez, Egilius L. H. Spierings
Format
Taschenbuch
Erscheinungsjahr
2012
Zusätzliche Produkteigenschaften
Hörbuch
No
Inhaltsbeschreibung
Paperback
Item Length
25cm
Item Height
10mm
Item Width
17cm
Buchreihe
Progress in Inflammation Research
Item Weight
366g
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