1. General Aspects.- Prognostic Factors and Nosological Criteria of Breast Cancer from the Pathologist¿s Point of View.- Growth Rate of Tumours and Natural Life Expectancy.- The Reporting of Non-significant Results in Clinical Trials.- Notes on Clinical Trial Methodology.- 2. Design and Performance of Clinical Trials.- The Cardiff Mastectomy Trial.- Experiences from a Multicentric Trial of Adjuvant Chemotherapy.- Thirty Years Experience with Breast Cancer Clinical Trials at the Christie Hospital in Manchester ¿ Clinical Aspects.- Thirty Years Experience of Breast Cancer Trials in Manchester ¿ Statistical Aspects.- The King¿s/Cambridge Trial.- Operable Breast Cancer with Positive Axillary Nodes: The Experience of the Milan Cancer Institute.- 3. Treatment Departures.- Problems in Withdrawal of Patients in a Randomized Study, when Treatment in One of the Groups Cannot be Carried Out.- Treatment Departure and Survival Analysis in a Randomized Trial on the Value of Pre- and Postoperative Radiotherapy in Breast Cancer.- 4. Stochastic Models.- Stochastic Models in Clinical Trials.- 5. Regression Models.- Aspects of the Cox Model in the Analysis of Survival Data.- Time Dependend Covariates.- A Large Sample Study of the Estimate for the Survival Distribution in Cox¿s Regression Model.- 6. Competing Risks.- Comparing Treatments, Adjusting for Competing Risks.- Why the Present Approach to Competing Risks Should be Abandoned.- Competing Risk Models in Early Breast Cancer Trials.- 7. Log Rank Test.- Some Extensions of the Log Rank Test.- Discussion.- Appendix Controlled Illness Processes with Incomplete Information ¿ A Re-examination of the Basic Hypothesis in Constructing Stochastic Models P. Tautu.- List of Participants.
Produktkennzeichnungen
Herausgeber
I. Armbruster, H. R. Scheurlen, G. Weckesser
ISBN-10
3540095306
ISBN-13
9783540095309
eBay Product ID (ePID)
165806284
Produkt Hauptmerkmale
Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
292 Seiten
Verlag
Springer Berlin Heidelberg, Springer Berlin
Publikationsname
Clinical Trials in 'early' Breast Cancer
Autor
I. Armbruster, H. R. Scheurlen, G. Weckesser
Format
Taschenbuch
Erscheinungsjahr
1979
Zusätzliche Produkteigenschaften
Hörbuch
No
Inhaltsbeschreibung
Paperback
Item Length
23cm
Item Height
1cm
Item Width
15cm
Nummer Innerhalb der Serie
4
Buchreihe
Lecture Notes in Medical Informatics
Item Weight
446g
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