Produktinformation
Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.Produktkennzeichnungen
HerausgeberCandace S. Johnson, Donald L. Trump
ISBN-101489982647
ISBN-139781489982643
eBay Product ID (ePID)205582390
Produkt Hauptmerkmale
VerlagSpringer Us, Springer New York
Erscheinungsjahr2014
Anzahl der Seiten356 Seiten
PublikationsnameVitamin D And Cancer
SpracheEnglisch
ProduktartLehrbuch
AutorDonald L. Trump, Candace S. Johnson
FormatTaschenbuch
Zusätzliche Produkteigenschaften
HörbuchNo
InhaltsbeschreibungPaperback
Item Height1cm
Item Length23cm
Item Weight540g
Item Width15cm