Das Gehirn in Bewegung: Von Mikroschaltungen zur globalen Gehirnfunktion von Grillner-

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The Brain in Motion: From Microcircuits to Global Brain Function by Grillner
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Book Title
The Brain in Motion: From Microcircuits to Global Brain Function
Publication Date
2023-10-31
Pages
286
ISBN
9780262048200
Kategorie

Über dieses Produkt

Product Identifiers

Publisher
MIT Press
ISBN-10
0262048205
ISBN-13
9780262048200
eBay Product ID (ePID)
25059001980

Product Key Features

Number of Pages
286 Pages
Language
English
Publication Name
Brain in Motion : from Microcircuits to Global Brain Function
Subject
Neuroscience, Life Sciences / Neuroscience, Life Sciences / Biology
Publication Year
2023
Type
Textbook
Subject Area
Science, Medical
Author
Sten Grillner
Format
Hardcover

Dimensions

Item Height
0.7 in
Item Weight
16.2 Oz
Item Length
9 in
Item Width
6 in

Additional Product Features

Intended Audience
Trade
LCCN
2022-054177
TitleLeading
The
Illustrated
Yes
Table Of Content
Preface ix 1 THE VERTEBRATE MOTOR REPERTOIRE AND THE EVOLUTION OF THE BRAIN 1 1.1 Introduction 1 1.2 Vertebrate Motor Behavior from Lamprey to Humans: Overview in an Evolutionary Perspective 3 1.3 The Basic Building Blocks of Behavior: Motor Programs and Their Selection--Overview 21 1.4 The Blueprint of the Vertebrate Motor System Is 500 Million Years Old 27 2 EXECUTION OF MOVEMENT: A PALETTE OF CPGS AND MOTOR CENTERS FROM MIDBRAIN TO SPINAL CORD 39 2.1 Introduction 39 2.2 CPG Networks Producing Locomotor, Respiratory, and Chewing Movements and Related Behaviors 40 2.3 A Brainstem Center for Coordination of Reaching and Grasping Movements in the Lateral Reticular Medulla 66 2.4 The PAG Channels Commands from the Hypothalamus and Amygdala 71 2.5 Integration of Innate Motor Programs in Daily Life: Skilled Aspects of the Control of Motion 78 2.6 Conclusion 80con 3 THE VERTEBRATE SOLUTION FOR ACTION IN THE EGOCENTRIC SPACE: MULTISENSORY INTEGRATION IN THE TECTUM/SUPERIOR COLLICULUS 81 3.1 Introduction 81 3.2 Multisensory Representation of the Surrounding Space in the Tectum/SC 82 3.3 Tectum/SC Control of Eye, Orienting, and Evasive Movements 89 3.4 Conclusion 96 4 THE ROLES OF THE BASAL GANGLIA: FOR INITIATION OF MOVEMENT AND MOTOR LEARNING 97 4.1 Overview: The Relation between the Cortex and the Basal Ganglia 97 4.2 Basal Ganglia: Organization 101 4.3 Synaptic Interaction within the Striatum 117 4.4 Integrated Function of the Basal Ganglia 127 4.5 Dysfunction of the Basal Ganglia: Parkinson's and Huntington's Diseases and Other Conditions 143 4.6 The Contribution of the Basal Ganglia to the Selection of Action and the Control of Movement Amplitude 153 4.7 The Organization of the Basal Ganglia Is Conserved from Lampreys to Primates 160 5 THE ROLE OF THE CORTEX IN THE CONTROL OF MOVEMENT 165 5.1 Introduction 165 5.2 Somatosensory and Visuomotor Coordination Critical in the Preparatory Phase and the Transition between Diferent Commands in a Motor Sequence 168 5.3 The Motor Areas in the Frontal Lobe of Primates and Other Vertebrates 175 5.4 Neocortical Organization at the Cellular Level and the Interaction between the Frontal Motor Areas, Striatum, and Downstream Motor Targets 189 5.5 Motor Capacity after Lesions to the Neocortex, Including the Motor Cortex 197 5.6 Cortical Control of Robotic Arms via the Brain-Machine Interface after Spinal Cord Injury 200 5.7 Concluding Remarks: The Neocortex and the Control of Movement 201 6 THE CEREBELLUM: CONTRIBUTES TO THE PERFECTION OF COORDINATION 203 6.1 Introduction 203 6.2 The Cerebellar Circuitry 203 6.3 Spinal Cord Interaction with the Cerebellum: Locomotion and Other Movements 210 6.4 The Cerebellum and the Vestibulo-Ocular and Optokinetic Reflexes: Calibration of Motor Action 215 6.5 Parallel Fiber Synapses onto Purkinje Cells: Active and Silent Synapses-- Plasticity 218 6.6 The Cerebellum's Role for Learning to Associate Two Related but Independent Processes: Conditioned Reflexes 219 6.7 Modeling and Simulation of the Cerebellar Circuitry 219 6.8 Concluding Remarks: The Overall Role of the Cerebellum 220 7 COMMENTS ON WHAT WE HAVE LEARNED AND THE CHALLENGES AHEAD 223 7.1 "To Move or Not to Move," a Question Answered by the Basal Ganglia in Close Interaction with the Cortex 224 7.2 The Major Organizational Building Blocks of Motion 226 7.3 The Role of the Cerebellum: The Perfection of Coordination 226 7.4 Some Challenges Ahead 227 References 231 Index 261
Synopsis
An evolutionary perspective-from lampreys to humans-on how the forebrain coordinates movement while the networks in the brainstem and spinal cord handle the execution. All living creatures interact with their environment- even the most basic have a set of innate motor circuits they rely on to feed, locomote, fight, and flee. In The Brain in Motion , Sten Grillner describes the evolution of the motor repertoire of vertebrates, from protovertebrates to primates. With breadth and depth, Grillner explores how the brain uses the different microcircuits in the brainstem and spinal cord, coordinating them through commands from the forebrain. He also considers the normal function of the brain as a platform for understanding clinical conditions such as stroke, Parkinson s and Huntington s diseases, and spinal cord injury. Grillner also explains in The Brain in Motion how the remarkable finding that the lamprey forebrain has all the components of the mammalian one has radically changed scientists' views on the evolutionary origin of the vertebrate forebrain. We now know that the basic organization evolved 560 rather than 300 million years ago, as was previously thought. The forebrain, says Grillner, is like an orchestra conductor, while the microcircuits, with their reaching, grasping, posture, locomotion, and numerous other patterns of behavior, correspond to the members of the orchestra. The conductor determines when each will be called into action. Providing an elegantly integrated perspective, The Brain in Motion is essential reading for anybody that works professionally with movement control and function and dysfunction, whether in basic research, clinically, or in the training of motor skills., An evolutionary perspective--from lampreys to humans--on how the forebrain coordinates movement while the networks in the brainstem and spinal cord handle the execution. All living creatures interact with their environment: even the most basic have a set of innate motor circuits they rely on to feed, locomote, fight, and flee. In The Brain in Motion , Sten Grillner describes the evolution of the motor repertoire of vertebrates, from protovertebrates to primates. With breadth and depth, Grillner explores how the brain uses the different microcircuits in the brainstem and spinal cord, coordinating them through commands from the forebrain. He also considers the normal function of the brain as a platform for understanding clinical conditions such as stroke, Parkinson s and Huntington s diseases, and spinal cord injury. Grillner also explains in The Brain in Motion how the remarkable finding that the lamprey forebrain has all the components of the mammalian one has radically changed scientists' views on the evolutionary origin of the vertebrate forebrain. We now know that the basic organization evolved 560 rather than 300 million years ago, as was previously thought. The forebrain, says Grillner, is like an orchestra conductor, while the microcircuits, with their reaching, grasping, posture, locomotion, and numerous other patterns of behavior, correspond to the members of the orchestra. The conductor determines when each will be called into action. Providing an elegantly integrated perspective, The Brain in Motion is essential reading for anybody that works professionally with movement control and function and dysfunction, whether in basic research, clinically, or in the training of motor skills.
LC Classification Number
QP301.G685 2023

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