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Agammaglobulinämie - 9783319372495-
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Standort: Aldershot, Vereinigtes Königreich
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eBay-Artikelnr.:356633502726
Artikelmerkmale
- Artikelzustand
- Book Title
- Agammaglobulinemia
- ISBN
- 9783319372495
Über dieses Produkt
Product Information
This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved based on both human and animal models. The pathogenesis and clinical presentation of X-linked agammaglobulinemia, caused by mutations in the BTK (Bruton's tyrosine kinase) gene, are then presented in detail, followed by descriptions of the clinical manifestations and molecular basis of the less frequent autosomal recessive and autosomal dominant forms of agammaglobulinemia. Patients' management in terms of respiratory complications, gammaglobulin replacement therapy and the potential value of novel experimental therapeutic strategies are discussed. The book's closing chapters offer a comprehensive and updated description of mutations in the BTK gene, and the expression and function of BTK in cells other than B cells.
Product Identifiers
Publisher
Springer International Publishing A&G
ISBN-13
9783319372495
eBay Product ID (ePID)
6046695196
Product Key Features
Number of Pages
119 Pages
Language
English
Publication Name
Agammaglobulinemia
Publication Year
2016
Subject
Medicine, Biology
Type
Textbook
Series
Rare Diseases of the Immune System
Format
Paperback
Dimensions
Item Height
235 mm
Item Weight
2117 g
Item Width
155 mm
Volume
4
Additional Product Features
Editor
Vassilios Lougaris, Alessandro Plebani
Country/Region of Manufacture
Switzerland
Artikelbeschreibung des Verkäufers
Rechtliche Informationen des Verkäufers
USt-IdNr.: GB 976952259
Die Mehrwertsteuer wird auf meinen Rechnungen separat ausgewiesen.
CRN: 06687355
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- u***t (2246)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufA smooth and professional transaction throughout. The item was exactly as described, clearly listed, and fairly priced. Communication from the seller was prompt, polite, and helpful, with dispatch confirmed quickly. The parcel was securely packaged and arrived in excellent condition, ahead of the expected delivery date. Care was taken at every stage of the process. I would be happy to buy from this seller again—many thanks for a reliable and well-handled sale.
- w***r (65)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufItem as described and despatched in quick time. Item arrived within 3 days and was well packaged. Item was much cheaper than I found elsewhere online. I had a query about my order and the seller responded on the same day and sorted everything out. Would happily buy from seller againAbsolute Swamp Thing by Alan Moore Vol. 3 - 9781779512192 (Nr. 314607417279)
- 0***1 (1207)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufThe book was described accurately and is in brand new condition. It was one of the cheapest new copies on EBay. It was posted in very secure cardboard packaging and was delivered quite quickly. To be honest, buyer communications weren’t great but I don’t massively care about them as long as I get the item - which I did.