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Leitfaden zur Entwicklung von Herzmedikamenten Hardcover Buch-
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eBay-Artikelnr.:226805006556
Artikelmerkmale
- Artikelzustand
- Artist
- Not Specified
- PublishedOn
- 2013-08-14
- Title
- Cardiac Drug Development Guide
- ISBN
- 9781489938282
Über dieses Produkt
Product Identifiers
Publisher
Humana Press
ISBN-10
1489938281
ISBN-13
9781489938282
eBay Product ID (ePID)
203492923
Product Key Features
Number of Pages
X, 431 Pages
Language
English
Publication Name
Cardiac Drug Development Guide
Publication Year
2013
Subject
Pharmacy
Type
Textbook
Subject Area
Medical
Series
Methods in Pharmacology and Toxicology Ser.
Format
Trade Paperback
Dimensions
Item Weight
29.6 Oz
Item Length
10 in
Item Width
7 in
Additional Product Features
Intended Audience
Scholarly & Professional
Dewey Edition
21
Reviews
"This book provides a comprehensive overview of many advanced procedures in cardiac pharmacology that should be useful for graduate students and academic scientists as well as researchers in the pharmaceutical and biotechnology drug industries. This is an excellent book for researchers with an interest in cardiac pharmacology. Chapters address a broad spectrum of therapeutic areas and discuss appropriate molecular, biochemical, and electrophysiological in vitro as well as in vivo approaches used in the investigation of cardiovascular pharmacology. Moreover, the book addresses current clinical therapeutic trends in cardiovascular medicine."-Doody's Health Sciences Book Review Journal "The scope of material covered is comprehensive, providing eclectic coverage of some very topical issues in cardiac biology and cardiac medicine...most of the chapters will be of interest to a much wider audience than pharmacologists...a worthwhile purchase." - Journal of Pharmacological and Toxicological Methods "This textbook is a comprehensive look into the latest in cardiovascular drug developments and novel therapeutic agents. It covers a broad spectrum of therapeutic areas including ionic channels, adenoviral vector delivery for cardiovascular gene therapy, pharmacometrics, and gender differences in heart failure and angiogenesis therapy in coronary heart disease. It would be useful for clinical researchers and pharmacologists in cardiac drug development. Research scientists, graduate students and pharmacologists involved in both the pharmaceutical and biotechnological drug industries would benefit from this book." - E-STREAMS
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
615/.71
Table Of Content
Cardiac Drug Development.- Novel Molecular Targets for Cardiac Drug Development.- The Role of Cardiac Pacemaker Currents in Antiarrhythmic Drug Discovery.- Oxygen Free Radicals in Heart Disease.- Mitogen-Activated Protein Kinases-Mediated Signaling in Cardiac Pathology.- Development of Anti-Inflammatory Drugs for Cardiovascular Disease.- Development and Use of Platelet Glycoprotein Antagonists in Heart Disease.- The Sodium-Hydrogen Exchange System in the Heart.- Nitric Oxide and Cardiac Ischemia.- Functional Endpoints Evaluating Cardiac Drug Activity.- Ionic Mechanisms of Atrial Fibrillation.- Targeting Ischemic Ventricular Arrhythmias.- Biochemical Mediators of Ventricular Arrhythmias in Ischemic Heart Disease.- Heterologous Expression Systems and Screening Technologies in Ion Channel Drug Discovery.- Molecular Diversity of Ion Channels in the Mouse Heart.- Delayed Protection of the Myocardium.- Clinical Aspects in Cardiac Drug Development.- Cardiac Troponin Testing for Detection of Myocardial Infarction.- A Genetic Basis for Cardiac Arrhythmias.- Myocardial Adenoviral Vector Delivery for Cardiovascular Gene Therapy.- The Role of Pharmacometrics in Cardiovascular Drug Development.- Gender Differences in Heart Failure.- Angiogenesis Therapies for Coronary Artery Disease.
Synopsis
Cardiac Drug Development Guide outlines, in detail, the therapeutics of cardiac medicine currently at the cutting edge of scientific research and development around the world. This volume integrates basic and clinical cardiac pharmacology by c- bining, for the first time, both classical and molecular aspects of therapeutic drug development. The chapters comprise a broad spectrum of therapeutic areas and hence involve a comprehensive discussion of molecular, biochemical, and electrophy- ological concepts based on years of in vitro as well as in vivo pharmacological st- ies. In addition, the latter part of the book includes comprehensive clinical cardiac chapters that describe important topics in molecular medicine. These chapters also discuss current clinical therapeutic trends in medicine and provide an evaluation of the efficacy of novel drugs in these areas. Cardiac Drug Development Guide has many distinctive and outstanding features that set it apart from other cardiac pharmacology books. This book introduces topics in an easily understandable format for researchers in many varying disciplines by integrating and thereby simplifying concepts not usually discussed across a broad range of cardiac disciplines and in a highly technical field. Each chapter not only introduces and describes the physiology, pharmacology, and pathophysiology of the disease, but also overviews the clinical implications of drug development, what stages these areas are currently in, and also reviews some of the methodologies involved in drug discovery and development. As a result, this book provides a comprehensive overview of the most advanced procedures in cardiac pharmacology today.
LC Classification Number
RS1-441
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