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Neuronal Guidance: the Biology of Brain Wiring by Alex Kolodkin (2010, Hardcover)

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Product Identifiers

PublisherCold Spring Harbor Laboratory Press
ISBN-100879698977
ISBN-139780879698973
eBay Product ID (ePID)99574949

Product Key Features

Number of Pages330 Pages
Publication NameNeuronal Guidance: the Biology of Brain Wiring
LanguageEnglish
Publication Year2010
SubjectNeuroscience
TypeTextbook
Subject AreaMedical
AuthorAlex Kolodkin
FormatHardcover

Dimensions

Item Height0.9 in
Item Weight36.3 Oz
Item Length9 in
Item Width7.3 in

Additional Product Features

Intended AudienceScholarly & Professional
LCCN2010-042322
Dewey Edition22
IllustratedYes
Dewey Decimal612.8
SynopsisDuring the development of the brain growing nerves send out neuronal processes (axons and dendrites) that connect them to other nerve cells, sensory organs, and muscle tissue. Correct targeting of these is the basis for wiring of the entire nervous system and depends on attractive and repulsive molecular cues that guide the developing neurons to the appropriate destination. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the mechanisms underlying neuronal guidance and branching and their roles in the development and function of the nervous system. The contributors examine the major guidance cues and their receptors, the intracellular signaling pathways they activate, and their function in the context of important phenomena such as laminar organization and dendrite spacing. Other chapters consider the roles of guidance cues in development of neuronal circuits dedicated to the processing of particular sensory stimuli, such as the visual and olfactory systems. In addition, they cover the roles played by guidance cues and their receptors in neuronal regeneration and human genetic disorders, revealing important clinical implications of work in this field. The book also contains chapters discussing the function of guidance molecules in other processes, such as neuronal cell body migration, axon pruning, and regulation of neuronal cell death. In addition, it explores their roles outside the nervous system for example, in development of the vasculature. This volume is thus of general interest to cell and developmental biologists, as well as all neurobiologists interested in how the nervous system develops and functions.
LC Classification NumberQP356.25.N48 2011

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