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FMOC Festphasenpeptidsynthese: Ein praktischer Ansatz (Praktischer Ansatz siehe,-
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eBay-Artikelnr.:186354893670
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- Artikelzustand
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- Hinweise des Verkäufers
- “Used book in good condition. Shows typical wear. Quick shipping. Satisfaction guaranteed!”
- ISBN
- 9780199637249
Über dieses Produkt
Product Identifiers
Publisher
Oxford University Press, Incorporated
ISBN-10
0199637245
ISBN-13
9780199637249
eBay Product ID (ePID)
1616047
Product Key Features
Number of Pages
370 Pages
Publication Name
Fmoc Solid Phase Peptide Synthesis : a Practical Approach
Language
English
Publication Year
2000
Subject
Life Sciences / Biochemistry, Chemistry / General
Type
Textbook
Subject Area
Science
Series
Practical Approach Ser.
Format
Uk-Trade Paper
Dimensions
Item Height
0.8 in
Item Weight
23.3 Oz
Item Length
9.2 in
Item Width
6.1 in
Additional Product Features
Intended Audience
College Audience
LCCN
99-041250
Dewey Edition
21
Reviews
'covers the essential procedures for the production of linear peptides, and the techniques for preparing cyclic, side-chain modified, phospho-and glycopeptides' Sciences de la vie'..a completly fresh book.....a goldmine...' European Petide Society, 'covers the essential procedures for the production of linear peptides, and the techniques for preparing cyclic, side-chain modified, phospho-and glycopeptides' Sciences de la vie
Series Volume Number
222
Illustrated
Yes
Dewey Decimal
547/.756
Table Of Content
PrefaceIntroduction - a retrospective viewpointBasic PrinciplesBasic ProceduresPreparation and Handling of Peptides Containing Methionine and CysteineDifficult PeptidesSynthesis of Modified PeptidesPhosphopeptide SynthesisGlycopeptide SynthesisConvergent Peptide SynthesisMethods of Preparing Peptide-carrier ConguatesChemoselective and Orthogonal Ligation TechniquesPurification of Large Peptides Using Chemioselective TagsInstrumentation for Automated Solid-Phase Peptide SynthesisManual Multiple Synthesis MethodsAppendix OneAppendix TwoAppendix ThreeIndex
Synopsis
In the years since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The basic problems outstanding at the time of publication of this earlier work have now been, for the most part, solved. As a result, innovators in the field have focussed their efforts to develop methodologies and chemistry for the synthesis of more complex structures. The focus of this new volume is much broader, and covers not only the essential procedures for the production of linear peptides but also more advanced techniques for preparing cyclic, side-chain modified, phospho- and glycopeptides. Many other methods also deserving attention have been included: convergent peptide synthesis; peptide-protein conjugation; chemoselective ligation; and chemoselective purification. The difficult preparation of cysteine and methionine-containing peptides is also covered, as well as methods for overcoming aggregation during peptide chain assembly and a survey of available automated instrumentation., Since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader, and covers the essential procedures., In the years since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The basic problems at the time of publication of this earlier work have now for the most part, been solved. As a result, innovators in the field have focussed their efforts to develop methodologies and chemistry for the synthesis of more complex structures. The focus of this new volume is much broader, and covers the essential procedures for the production of linear peptides and more advanced techniques for preparing cyclic, side-chain modified, phospho- and glycopeptides. Many other methods also deserving attention have been included: convergent peptide synthesis; peptide-protein conjugation; chemoselective ligation; and chemoselective purification. The difficult preparation of cysteine and methionine-containing peptides is also covered, as well as methods for overcoming aggregation during peptide chain assembly. Many of the techniques developed for the production of large arrays of peptides by parallel synthesis, such as t-bag, SPOT and PIN synthesis, have naturally been included. Finally, a survey of available automated instrumentation has also been provided.
LC Classification Number
QD431.25.S93F66 2000
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