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Galvani's Spark: The Story of the Nerve Impulse by Alan McComas
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Standort: Vinton, Virginia, USA
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eBay-Artikelnr.:154427433509
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- “No writing. At some point the book has gotten wet. Great chance to get a deal.”
- ISBN
- 9780199751754
Über dieses Produkt
Product Identifiers
Publisher
Oxford University Press, Incorporated
ISBN-10
0199751757
ISBN-13
9780199751754
eBay Product ID (ePID)
102852151
Product Key Features
Number of Pages
416 Pages
Publication Name
Galvani's Spark : the Story of the Nerve Impulse
Language
English
Subject
Neurology, Neuroscience, Life Sciences / Neuroscience, History
Publication Year
2011
Type
Textbook
Subject Area
Science, Medical
Format
Hardcover
Dimensions
Item Height
1.2 in
Item Weight
23.3 Oz
Item Length
6.5 in
Item Width
9.3 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2010-049113
Dewey Edition
22
Reviews
"Galvani's Sparkis an outstanding work of scholarship which will unquestionably prove to be a treasure house, as it is bursting with information, with scientific detail and with innumerable fascinating illustrations and references to the relevant literature. To do it full justice would almost require me to write another comprehensive volume, as this work embraces not only a vast amount of detailed scientific information, but also includes a number of delicious personal vignettes relating to the work, activities and views of many of the glitterati of neuroscience. In my opinion this book is a colossal achievement which will be widely read and enjoyed, not only by physiologists, but also by people like myself who have spent a lifetime in neurological practice." -- John Walton (Lord Walton of Detchant) Kt TD, MA, MD, DSc, FRCP, FMedSci, Former Professor of Neurology and Dean of Medicine, University of Newcastle upon Tyne , Belford, Northumberland, UK "This excellent historical survey covers a fundamental area of modern neuroscience and neurobiology, namely the generation of the nerve impulse. McComas writes in a popular style with amusing anecdotes and his own commentaries and opinions, but there is no sacrifice of accuracy or erudition. It is all very easy to read. It should be widely enjoyed by neuroscientists, including those, now in the majority, who have grown up with little or no acquaintance with electrophysiology; indeed, it is entirely suitable for anybody interested in the way nerves work. McComas incidentally provides a serious teaching text by explaining and putting into context the major experiments underlying current understanding of the nerve impulse and synaptic transmission; thus he provides a stimulating introduction for both honours and doctoral students.Galvani's Sparkcan be warmly recommended." -- Peter Matthews MD, DSc, FRS, Emeritus Professor of Sensorimotor Physiology, Oxford University, UK "Alan McComas has made very significant scientific contributions in neurophysiology and in the estimation of motor units in particular. Remarkably he has been able to explain the story of the nerve impulse in a clear and engaging narrative which has some similarities to a detective story. This approach brings to life the triumphs, sacrifices and disappointments in the progress of knowledge and discovery. Imperfect scientists have contributed to our understanding of this story which relates to every one of us. I believe this book will become a classic and it is a remarkable achievement." -- Dr. Adrian R.M. Upton M.B., B.Chir., FRCP(C), FRCP(E), FRCP(G), Professor, Department of Medicine, Division of Neurology, McMaster University, Hamilton, ON, Canada "Physiologists, regardless of specialization, will find Alan McComas' scholarly presentation of 'the wonders of the nerve impulse' to be a captivating example of making history interesting, alive, and at times, exciting." -- Charles M. Tipton, PhD, Emeritus Professor of Physiology, University of Arizona, Tucson, AZ "The year 1953 is renowned in Science for the discovery of the molecular basis of inheritance by Crick and Watson at Cambridge University. Alan McComas proposes and ably supports the thesis in Galvani's Spark, that in the preceding year at the same university, Hodgkin and Huxley made a comparable leap in the understanding of the membrane basis of the initiation and conduction of the nerve impulse." -- Professor Vahe E. Amassian, Department of Physiology and Pharmacology, State University of New York-Downstate Medical Center, Brooklyn, NY
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
616.8/047547
Table Of Content
Contents Glossary of Terms and Abbreviations Chapter 1: Introduction Chapter 2: The Spark Chapter 3: Catching Up Chapter 4: The Anatomist's Eye Chapter 5: Cambridge, 1904. The Engineer Chapter 6: The Cathode Ray Oscilloscope Chapter 7: The Code Chapter 8: Excitation and Inhibition Chapter 9: The Messengers Chapter 10: The Squid Giant Axon Chapter 11: The Neuromuscular Junction Chapter 12: The Giant Axon Impaled Chapter 13: The War Years Chapter 14: Sodium Unmasked Chapter 15: The Voltage Clamp Chapter 16: Aftermath Chapter 17: Muscle: the New Physiology Chapter 18: More Triumphs with Microelectrodes Chapter 19: The Single Ion Channel Chapter 20: Myotonic Goats and Migraines Chapter 21: The Swinging Gate Chapter 22: Departures Chapter 23: Postscript Notes Bibliography Index
Synopsis
Galvani's Spark describes the gradual understanding of the nerve impulse--the basis of all thoughts, sensations and actions. Proceeding from a chance observation on a frog leg, to studies on squid giant axons and bacteria, this book concludes with the increasing realization that ion channells are responsible for a variety of clinical disorders. Written by a neurophysiologist, the book provides portraits of some of the greatest names in medical science., Galvani's Spark chronicles the gradual understanding of the nerve impulse which is the basis of all thoughts, sensations and actions. The story begins with Luigi Galvani's chance observation of a spark from a friction machine causing a frog's leg to twitch from across the room. The accurate recording and the understanding of the properties of the nerve fiber membrane that makes the impulse possible became the objectives of neuroscientists for over 200 years. The author, Alan J. McComas finely interweaves the stories, the challenges, and the controversies of the most prominent figures in neuroscience, from the histological descriptions of nerve cells by Cajal to the discovery of a three-dimensional structure of ion channels in cell membranes by MacKinnon. Along the way he details the first recordings of the impulse with a cathode ray oscilloscope by Gasser and Erlanger, Adrian's discovery that stimulus intensity is coded by the frequency of nerve impulses, and Hodgkin and Huxley's brilliant voltage clamp experiments, amongst many others. The recognition by Galvani that muscles and nerves have an electrical component triggered the field of neurophysiology and in turn has produced some of the greatest discoveries in neuroscience. 16 investigators of the nerve impulse went on to win or share Nobel prizes and this book not only emphasizes their work but also traces their brilliant careers. For anyone interested in the nervous system and the history of neuroscience, Galvani's Spark: The Story of the Nerve Impulse is essential reading.
LC Classification Number
QP363.M385 2011
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Sirgleems Garage
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- 0***h (1526)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufSwift shipping. Item arrived in "very good" condition. However, there were some stickers on the dust jacket that were not apparent in the photo. They were difficult to removed, but I did get them off. The pages of the book are "like new". Highly recommended eBay seller.In Search of the Mountain of God: The Discovery of the Real Mt. Sinai, Very Good (Nr. 166047275294)
- c***r (20)- Bewertung vom Käufer.Letztes JahrBestätigter KaufOutstanding eBay experience! Fast shipping, excellent packaging, and the item arrived exactly as described. Great value for the price—highly recommended seller!Sony Distribution Center Free Tape Offer Mailer 3-703-392-01(1) (Nr. 154800091556)
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