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Brain Fables-
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Standort: North Smithfield, Rhode Island, USA
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eBay-Artikelnr.:146539768811
Artikelmerkmale
- Artikelzustand
- Release Year
- 2020
- Book Title
- Brain Fables
- ISBN
- 9781108744621
Über dieses Produkt
Product Identifiers
Publisher
Cambridge University Press
ISBN-10
1108744621
ISBN-13
9781108744621
eBay Product ID (ePID)
16038520473
Product Key Features
Number of Pages
174 Pages
Publication Name
Brain Fables : the Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them
Language
English
Subject
Neurology, Internal Medicine
Publication Year
2020
Type
Textbook
Subject Area
Medical
Format
Trade Paperback
Dimensions
Item Height
0.4 in
Item Weight
11.6 Oz
Item Length
9.2 in
Item Width
6.1 in
Additional Product Features
Intended Audience
Trade
LCCN
2020-004122
Dewey Edition
23
Reviews
'This book attempts to incorporate overarching scientific themes with a detailed overview of pathophysiology and clinical features of Parkinson's disease. The chapters examine clinical features, subtypes and progression of the disease, ways of looking at the disease scientifically, a comparison to oncology, and a review of disease modifying treatments versus symptomatic treatment. The diagrams and tables are outstanding and the production values are excellent. The book, however, is limited by the attempt to tackle big concepts for a more lay public with very technical writing, an unimaginative look at theory and facts, and the distinctly different styles between the two authors.' Rohit Das, Doody's Book Review Service
Illustrated
Yes
Dewey Decimal
616.8
Table Of Content
Preface; Acknowledgements; 1. The shaky six and the 'second reality'; 2. Pieces of a puzzle?; 3. Disease 'redefinition': a tough pill to swallow; 4. Disease subtypes: the promise and the fallacy; 5. Protein paradox; 6. The fault in our models; 7. Biomarkers: the promise and the fallacy; 8. Lessons from oncology; 9. Symptomatic vs. disease-modifying therapies; 10. The hypothesis that refuses to die; 11. Our living dissonance; 12. The scientific and lay narratives; 13. Challenges viewed from afar; 14. The moonshot: population-based studies of aging; 15. Predictions for the 2020s and beyond; Epilogue. 'When will we have a cure for Parkinson's disease?"; Note added at press time; References; Index.
Synopsis
For neurodegenerative diseases such as Parkinson's and Alzheimer's there is no unifying biology, explaining why every attempt to cure them has failed. This book provides a blueprint for a new way of thinking, eliminating misleading diagnostic labels and enabling the development of effective therapies, one biological subtype at a time., An estimated 80 million people live with a neurodegenerative disease. That number is expected to increase rapidly as populations age, lifespans increase, and exposure to toxins rises. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. This is because diseases such as Parkinson's and Alzheimer's do not exist in biology. Yet, hundreds of clinical trials around the world are examining the potential of single therapies in thousands of people sharing one of these labels. Compounding the problem, these therapies were developed on evidence from models that do not come close to capturing the complexity of these diseases in the affected humans. These practices must end. Brain Fables is a call to refocus on understanding living and aging to create the personalized treatments each affected individual desperately needs.
LC Classification Number
RC365.E87 2020
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