Das erste Gehirn: Die Neurowissenschaften der Planarien
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Das erste Gehirn: Die Neurowissenschaften der Planarien-
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- 9780199965045
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- 9780199965045
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Oxford University Press, Incorporated
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0199965048
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9780199965045
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201607173
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Book Title
First Brain : the Neuroscience of Planarians
Number of Pages
280 Pages
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English
Publication Year
2014
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Neuroscience, Life Sciences / Neuroscience, Life Sciences / General, Life Sciences / Zoology / Invertebrates
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Science, Medical
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Hardcover
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2013-031621
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The
Reviews
"There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagàn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own "I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology "In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun "The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice "The inaugural brain, belonging to flatworms, is the eponymous excuse for Oné Pagán's delightful book, The First Brain..." --Peggy Mason, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading On Pagn's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagn's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own "I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology "In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun "The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice "The inaugural brain, belonging to flatworms, is the eponymous excuse for On Pagn's delightful book, The First Brain..." --Peggy Mason, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book,Pagàn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University"Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs"Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) notrecalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very,Very Different from Our Own"I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology"In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun"The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice"The inaugural brain, belonging to flatworms, is the eponymous excuse for Oné Pagán's delightful book, The First Brain..." --Peggy Mason, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagàn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own "I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology "In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagà n has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own"I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology"In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun"The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice"The inaugural brain, belonging to flatworms, is the eponymous excuse for Oné Pagán's delightful book, The First Brain..." --Peggy Mason, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagàn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own"I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology"In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun"The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice"The inaugural brain, belonging to flatworms, is the eponymous excuse for Oné Pagán's delightful book, The First Brain..." --Peggy Mason, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading OnPagn's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagn's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own "I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology "In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun "The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice "The inaugural brain, belonging to flatworms, is the eponymous excuse for OnPagn's delightful book, The First Brain..." --Peggy Mason, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagàn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own "I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology, "There are few good books about the evolution of the brain, but this is one of those few -- a journey along an ancient byway of the animal kingdom which shows just how blinkered and vertebrate-obsessed neuroscience has become. In The First Brain we learn that planarians have an array of frankly bizarre features with very real implications for the origins of our own cerebral majesty. By the end of this appealingly personal and reflective book, Pagàn has cogently argued that it is only by studying his favorite cannibalistic worm that we can truly understand ourselves." --David Bainbridge, University Clinical Veterinary Anatomist, Cambridge University "Flatworms are about as alien to us as an animal can be, but they finally have an ambassador. Pagan's engaging book walks us through why flatworms aren't aliens at all, and why they have the distinction of being the first animals on Earth having a "brain." ...A brain in many respects like our own." --Mark Changizi, 2ai Labs "Reading Oné Pagán's The First Brain is a pleasure akin to sitting in the company of an especially engaging and erudite scientist as he tells of research (his own and others) on his favorite subject: in this case, the wondrous animals you and I call flatworms and biologists call planarians. Dr. Pagán's enthusiasm for science, neurobiology and the aforementioned creatures is utterly contagious. If you begin the book (like me) not recalling exactly what a planarian is, you'll close it wondering why you and everyone you know aren't talking, thinking and writing about them all the time." --David Toomey, author of Weird Life: The Search for Life That is Very, Very Different from Our Own "I highly recommend this book to any clinical pediatric neurologist, neuropathologist, or basic neuroscientist with an interest in evolution and who keeps an open mind toward novel phylogenetic perspectives of the origin of the human nervous system, in addition to the novel practical research opportunities provided by this unique animal." --Journal of Child Neurology "In this book, Professor Pagan is an engaged and excited teacher about these fascinating little worms. ... Pagan writes with prose as clear as glass, and is able to bring even centuries-old insights on flatworms into the light. --Arrow Through the Sun "The author's enthusiasm, humor, and conversational writing style make for an enjoyable and intriguing read that should interest science enthusiasts and professionals alike. ... The First Brain is a fun and interesting work that makes a plausible case for the effective use of planarians in biomedical studies. Highly recommended." --Choice
Table Of Content
IntroductionPart I - Fundamentals1. ScienceScience does not existReductionism, its advantages and limitsOn theories and TheoriesEvolution and Life2. Biomedical ResearchBiochemistry and cell biology liteHow we classify lifeAnimal models and biomedical researchBasic or fundamental research?Part II - The Science of the Brain3. An introduction to neuroscienceNeuroscience or neurobiology?NeuronsThe Spaniard and the ItalianExcitable cells and electrophysiologySynapses and chemical neurotransmissionIs a nervous system absolutely necessary for survival?Plant Neurobiology4. The human brainWhat exactly is a brain?The human brain and nervous systemA brief history of what people thought of their brainsThe complexity of the human brain / On really BIG numbers5. Some brief thoughts on pharmacologyWhat is pharmacology?Psychopharmacology, plant styleAnimal models in pharmacologyPart III - Planarians6. PlanariansWhat is a flatworm?Flatworm evolution and fossil recordsWhat is a planarian?Early works on planarians (1700-1800s)Planariologists: Three "personal" connections7. Planarians in modern biologyGeneticsFirst they liked planarians then they didn'tSages of regenerationOf planarians and genomes8. Planarians in the popular culture: The arts, science fiction, fantasy and humorPlanarians in the popular culturePlanaria: Poem by Dr. Lance LarsenPlanarian manPlanaria and the new Battlestar GalacticaFringeTwilightThe Big Bang TheoryDr. WhoPlanarian humorPart IV - The First Brain9. The first brainEarly, really early nervous systemsThe first huntersThe first brainWhy are planarians an excellent animal model in neuroscience?Very brief comments on protopsychology10. From corals and plants to planarians and ratsPlanarians in pharmacology: nicotine and cocaineThe beginnings of systematic planarian pharmacology researchThe Temple University teamThe joy of discoveryFrom corals and plants to planarians and ratsPlanarian research translated to vertebrates: What does it mean, and what it doesn'tWhat can the planarian brain teach us about our own?EpilogueReferences - BooksReferences - Articles
Synopsis
Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to regenerate lost body parts, including complete regeneration of the nervous system. If cut into pieces, each piece of the planarian can regenerate into a complete organism. They are also unique among invertebrates in that they display addiction-like behaviors to many drugs abused by humans. Because of these distinct neurological traits, the planarian is often used as an animal model in neurological research, being used most recently for developments in neuropharmacology.The First Brain is a discussion of how planarians have been used in neuropharmacology, and what role they have played in scientific developments that have a high impact on our culture. Planarians have been the animal models for research in drug addiction, antidepressant development, and various other topics in biology, neurobiology, and even zoology. Pagán uses these flatworms as a framework to explore the history of biological research. The book provides accessible background information on how biomedical research is impacted by evolution, and defines neurobiology and neuropharmacology in ways that are easy to understand. At the same time, Pagán provides enough detail for the book to useful for scientists working in various subsections of biology. The planarian has played a key role in the history biological, neuropharmacological, and zoological research, and has even made appearances in a few unexpected places in popular culture. Oné Pagán explores all these roles, and shows us why the planarian truly is one of the most extraordinary and influential organisms in scientific research today., Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to regenerate lost body parts, including complete regeneration of the nervous system. If cut into pieces, each piece of the planarian can regenerate into a complete organism. They are also unique among invertebrates in that they display addiction-like behaviors to many drugs abused by humans. Because of these distinct neurological traits, the planarian is often used as an animal model in neurological research, being used most recently for developments in neuropharmacology. The First Brain is a discussion of how planarians have been used in neuropharmacology, and what role they have played in scientific developments that have a high impact on our culture. Planarians have been the animal models for research in drug addiction, antidepressant development, and various other topics in biology, neurobiology, and even zoology. Pagán uses these flatworms as a framework to explore the history of biological research. The book provides accessible background information on how biomedical research is impacted by evolution, and defines neurobiology and neuropharmacology in ways that are easy to understand. At the same time, Pagán provides enough detail for the book to useful for scientists working in various subsections of biology. The planarian has played a key role in the history biological, neuropharmacological, and zoological research, and has even made appearances in a few unexpected places in popular culture. Oné Pagán explores all these roles, and shows us why the planarian truly is one of the most extraordinary and influential organisms in scientific research today., The story of planarians, and their use as an animal model for many types of research in neuropharmacology. The book shows how research involving planarians has led to developments in biomedicine, neurobiology, and how planarians have been involved in popular biological and cultural topics., Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to regenerate lost body parts, including complete regeneration of the nervous system. If cut into pieces, each piece of the planarian can regenerate into a complete organism. They are also unique among invertebrates in that they display addiction-like behaviors to many drugs abused by humans. Because of these distinct neurological traits, the planarian is often used as an animal model in neurological research, being used most recently for developments in neuropharmacology. The First Brain is a discussion of how planarians have been used in neuropharmacology, and what role they have played in scientific developments that have a high impact on our culture. Planarians have been the animal models for research in drug addiction, antidepressant development, and various other topics in biology, neurobiology, and even zoology. Pag n uses these flatworms as a framework to explore the history of biological research. The book provides accessible background information on how biomedical research is impacted by evolution, and defines neurobiology and neuropharmacology in ways that are easy to understand. At the same time, Pag n provides enough detail for the book to useful for scientists working in various subsections of biology. The planarian has played a key role in the history biological, neuropharmacological, and zoological research, and has even made appearances in a few unexpected places in popular culture. On Pag n explores all these roles, and shows us why the planarian truly is one of the most extraordinary and influential organisms in scientific research today., Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to regenerate lost body parts, including complete regeneration of the nervous system. If cut into pieces, each piece of the planarian can regenerate into a complete organism. They are also unique among invertebrates in that they display addiction-like behaviors to many drugs abused by humans. Because of these distinct neurological traits, the planarian is often used as an animalmodel in neurological research, being used most recently for developments in neuropharmacology.The First Brain is a discussion of how planarians have been used in neuropharmacology, and whatrole they have played in scientific developments that have a high impact on our culture. Planarians have been the animal models for research in drug addiction, antidepressant development, and various other topics in biology, neurobiology, and even zoology. Pagán uses these flatworms as a framework to explore the history of biological research. The book provides accessible background information on how biomedical research is impacted by evolution, and defines neurobiology andneuropharmacology in ways that are easy to understand. At the same time, Pagán provides enough detail for the book to useful for scientists working in various subsections of biology. The planarian has played akey role in the history biological, neuropharmacological, and zoological research, and has even made appearances in a few unexpected places in popular culture. Oné Pagán explores all these roles, and shows us why the planarian truly is one of the most extraordinary and influential organisms in scientific research today.
LC Classification Number
QP376.P29 2014
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- s***a (96)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufOriginal despatch of the book from Australia was delayed and I had to chase it up when it didn't arrive. The seller apologised and offered a refund but I opted to wait. The missing book was then sturdily packed, speedily despatched, and arrived quickly and in pristine condition so I am happy I waited. Though they got off to a bad start, the seller redeemed themselves and I would buy from them again.The Amber Owl by Juliet Marillier [Paperback, 416 pages] (Nr. 167406523405)
- 1***d (10156)- Bewertung vom Käufer.Letzter MonatBestätigter KaufQuiried where the order was after nearly two weeks, was told it was sent by various operatives, it was marked as dispatched, then I was told I’d get a full refund as suppliers could not supply, but book was still listed but now at a higher price. Once I chased up the refund I was refunded and had to buy the book elsewhere. Disappointed-Yes, confused with conflicting statements-Yes, fully refunded-Yes, had to buy elsewhere-Yes. Other buyers warn of caution, I should have taken this warning!
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- r***7 (829)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufThis Seller is the Very Best. From First Contact to Delivery no one can surpass how Fantastic they are. Expertly Packed item, Fast Delivery and arrived in Perfect Condition. The price charged was competitive but not greedy and the postage the cost you would expect. They answered any enquiries quickly and full of the right information. I am so very, very pleased with this purchase and the Brrrrrilliant Seller. Thank you so very, very much. Keep doing what you are doing. Fantastic!Mending the Motocross Champion by Jean C. Gordon [Paperback] (Nr. 167190986672)
- s***a (96)- Bewertung vom Käufer.Letzte 6 MonateBestätigter KaufOriginal despatch of the book from Australia was delayed and I had to chase it up when it didn't arrive. The seller apologised and offered a refund but I opted to wait. The missing book was then sturdily packed, speedily despatched, and arrived quickly and in pristine condition so I am happy I waited. Though they got off to a bad start, the seller redeemed themselves and I would buy from them again.The Amber Owl by Juliet Marillier [Paperback, 416 pages] (Nr. 167406523405)
- 1***d (10156)- Bewertung vom Käufer.Letzter MonatBestätigter KaufQuiried where the order was after nearly two weeks, was told it was sent by various operatives, it was marked as dispatched, then I was told I’d get a full refund as suppliers could not supply, but book was still listed but now at a higher price. Once I chased up the refund I was refunded and had to buy the book elsewhere. Disappointed-Yes, confused with conflicting statements-Yes, fully refunded-Yes, had to buy elsewhere-Yes. Other buyers warn of caution, I should have taken this warning!