The present text book prove to be a great source of help, guidance and inspiration to the budding researcher in various universities belonging for the role of neurotransmitters. Particular attention has been paid to the development of each chapter thoughtfully and meticously, in its usual unique style of presentation, to provide sufficient well documented, systematically arranged and easily understandable lucid language. so that the senior students may get the maximum advantage of its value-added reading text material.d. Clearly the knowledge of the precise ultra structural of these transporters should have clear understanding of their implications in the physiological and pathophysiological functioning of specific synapses. On the other hand, addition ,alteration or deletion of genes encoding the transporters allow the generation of animal models that are considerable.