This volume contains the papers presented at the Inter national Symposium on "Cirrhosis, Hepatic Encephalopathy and Ammonium Toxicity", held in Valencia, Spain, November 27-29, 1989. Hepatic cirrhosis as well as other liver failures usual ly lead to hepatic encephalopathy which is an important cause of death in occidental countries. However the molecular bases of the pathogenesis of hepatic encephalopathy remain unclear and several hypotheses have been proposed. Hyperammonemia is considered one of the main factors responsible for the mediation of hepatic encephalopathy. Therefore, a part of the book is devoted to the effects of hyperammonemia on cerebral function, ammonia and amino acid metabolism, brain microtobules, astrocytes and synaptic trans mission and their possible role in the pathogenesis of hepatic encephalopathy. Carnitine has a remarkable protective effect against acute ammonium intoxication. Thus some results regarding this effect are also presented, as well as the clinical use of car nitine. The alterations of the metabolism of ammonia and of seda tives in liver diseases and their clinical implications are also discussed. The possible role of altered GABA-ergic neurotransmission on the pathogenesis of hepatic encephalopathy has received considerable attention recently. Results of these studies and those on benzodiazepine receptor ligands are presented as well as those on the hypothesis of the role of altered synaptic plasma membrane on the pathogenesis of hepatic encephalopathy.
Produktkennzeichnungen
Herausgeber
Vicente Felipo, Santiago Grisolía, Maria-Dolores Miñana
ISBN-10
1468458280
ISBN-13
9781468458282
eBay Product ID (ePID)
175502815
Produkt Hauptmerkmale
Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
288 Seiten
Verlag
Springer Us
Publikationsname
Cirrhosis, Hepatic Encephalopathy, And Ammonium Toxicity
Autor
Vicente Felipo, Santiago Grisolía, Maria-Dolores Miñana
Format
Taschenbuch
Erscheinungsjahr
2012
Zusätzliche Produkteigenschaften
Hörbuch
No
Inhaltsbeschreibung
Paperback
Item Length
25cm
Item Height
1cm
Item Width
17cm
Nummer Innerhalb der Serie
272
Item Weight
547g
Buchreihe
Advances in Experimental Medicine And Biology
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