Rolle der Lipid-Hilfsstoffe bei der Modifikation der oralen und parenteralen Arzneimittelabgabe: Grundlegendes P-

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Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery: Basic P
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ISBN-13
9780471739524
Book Title
Role of Lipid Excipients in Modifying Oral and Parenteral Drug De
ISBN
9780471739524
Kategorie

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Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
0471739529
ISBN-13
9780471739524
eBay Product ID (ePID)
54361462

Product Key Features

Number of Pages
216 Pages
Language
English
Publication Name
Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery : Basic Principles and Biological Examples
Publication Year
2006
Subject
Life Sciences / Biochemistry, Pharmacy, Chemistry / Industrial & Technical
Type
Textbook
Subject Area
Science, Medical
Author
Kishor M. Wasan
Format
Hardcover

Dimensions

Item Height
0.8 in
Item Weight
17.5 Oz
Item Length
9.6 in
Item Width
6.4 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2006-019129
Dewey Edition
22
Illustrated
Yes
Dewey Decimal
615/.7
Table Of Content
Preface. Contributors. Chapter 1. Interaction of Drug Transporters with Excipients (K. Sandy Pang, Lichuan Liu, and Huadong Sun). Chapter 2. Formulation Issues around Lipid-Based Oral and Parenteral Delivery Systems (Seong Hoon Jeong, Jae Hyung Park and Kinam Park). Chapter 3. Lipid-Based Parenteral Drug Delivery Systems: Biological Implications (Vladimir P. Torchilin). Chapter 4. Principles in the Development of Intravenous Lipid Emulsions (Joanna Rossi and Jean-Christophe Leroux). Chapter 5. Protein adsorption patterns on parenteral lipid formulations-key factor determining the in vivo fate (Rainer H. Muller and Torsten M. Goppert). Chapter 6. Nanoparticle targeting for drug delivery across the blood brain barrier (James Egbert, Werner Geldenhuys, Fancy Thomas, Paul R. Lockman, Russell J. Mumper and David D. Allen). Chapter 7. Lipid-Coated Perfluorocarbon Nanostructures as Parenteral Therapeutic Agents (Evan C. Unger, Terry O. Matsunaga and Reena Zutshi). Index.
Synopsis
The principles and formulation of lipid-based drug delivery systems With its promise for improving drug absorption, the emerging field of lipid-based drug delivery systems has attracted considerable attention from academia to industry. Filling the need for a standard text on the subject, this book assembles a group of experienced investigators and educators from the front line of pharmaceutical sciences to provide a comprehensive resource on the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. Presenting a solid grounding in the fundamental principles of lipid absorption in the intestines and vascular body systems, the text gives readers in-depth insight into the formulation issues, such as dissolution testing and stability testing, and physiological and biopharmaceutical issues, including the role of specific enzymes, the evaluation of transport systems in the body, and the mechanisms governing the transport of water-insoluble drugs. Chapters cover: Interaction of drug transporters with excipients Formulation issues around lipid-based oral and parenteral delivery systems Biological implications of lipid-based parenteral drug delivery systems Principles in the development of intravenous lipid emulsions Protein adsorption patterns on parenteral lipid formulations a key factor determining the in vivo fate Nanoparticle targeting for drug delivery across the blood-brain barrier Lipid-coated perfluorocarbon nanostructures as parenteral therapeutic agents, Lipid-based drug delivery systems is an emerging field that uses lipids to make drugs more soluble in water and better able to function in the body., This comprehensive resource covers the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. It presents the principles of lipid absorption and covers formulation issues, such as dissolution testing and stability testing, and physiological and biopharmaceutical issues, including the role of specific enzymes, the evaluation of transport systems in the body, and the mechanisms governing the transport of water-insoluble drugs.
LC Classification Number
RS201.E87R65 2007

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